Abstract
<jats:p>Due to the development of insecticide resistance in synanthropic insects and vectors of human and animal pathogens, it is necessary to introduce new insecticides into rotation regimens. This review examines the feasibility and potential for the use of insecticides belonging to different groups based on their mechanism of action in medical pest control: 28 «Ryanodine receptor modulators», 29 «Chordotinal organ nicotinamidase inhibitors», and 30 «Allosteric modulators of GABA-dependent chloride channels». The following compounds are of interest: the diamides cyantraniliprole and chlorantraniliprole (Group 28), fluralaner and other isoxazolines (Group 30), and the meta-diamide broflanilide. The diamides meet all necessary hygienic standards and are effective against synanthropic insects. Fluralaner and other isoxazolines are used on warm-blooded animals and are highly effective against cockroaches and flies. Broflanilide is used in many countries worldwide for medical disinfestation. Involving these groups of insecticides in rotation schemes will contribute to overcoming the resistance of synanthropic insects to insecticides. Keywords: resistance, rotation, new insecticides, medical disinfestation, diamides, isoxazolines, meta-diamides.</jats:p>