Abstract
<jats:p>The article is devoted to the problem of predicting the risk and prevention of sudden cardiac death (SCD) in the general human population and in heart diseases. Approaches to SCD risk stratification at the population and individual levels based on clinical, instrumental, and genetic diagnostic and screening methods are discussed. Preventive and therapeutic strategies in the aspect of cardiac arrest and SCD are considered. The problem of determining the individual risk of SCD for individuals from the general population is currently difficult and has not been unequivocally solved. Stratification of the risk of ventricular tachyarrhythmias and SCD in high-risk patient groups allows to determine a preventive strategy. The basis of this strategy is the use of implantable cardioverter defibrillators. In the population of patients with heart failure, the use of optimal drug therapy can reduce the risk of general, cardiovascular, and sudden cardiac death. Early diagnosis of rare diseases (cardiomyopathies, channelopathies) will make it possible to inform about potential triggers of ventricular tachyarrhythmias, conduct timely recognition and confirmation of life-threatening arrhythmias, stratify the risk of SCD and determine a preventive treatment strategy.</jats:p>