Abstract
<jats:p> <jats:bold> Introduction <jats:italic>.</jats:italic> </jats:bold> Nosocomial meningitis (NM) is a rare but difficult-to-diagnose and treat complication of neurosurgical procedures. </jats:p> <jats:p> <jats:bold> Materials and methods <jats:italic>.</jats:italic> </jats:bold> A literature search and analysis was performed in the medical information systems PubMed and eLibrary, using the following keywords: nosocomial meningitis, postneurosurgical meningitis, surgical site infection (SSI), device-associated infection. </jats:p> <jats:p> <jats:bold> Results <jats:italic>.</jats:italic> </jats:bold> The main strategy for counteracting NM in neurosurgery represents an integrated approach to its prevention at all stages of the perioperative period. This approach includes strict adherence to aseptic rules, optimization of work with tissues and compliance with an adequate regimen of antibiotic prophylaxis; its implementation can reduce the risk of developing NM. Prolonged administration of antibacterial drugs in the postoperative period and their local administration into the surgical wound remain a subject of debate. </jats:p> <jats:p> <jats:bold> Conclusion <jats:italic>.</jats:italic> </jats:bold> An emphasis on perioperative preventive measures can reduce the incidence of NM and improve outcomes following neurosurgery. </jats:p>