Abstract
<jats:title>Abstract</jats:title> <jats:p>A variety of pathological and physiological states can be identified and differentiated through diagnostic procedures/laboratory studies. Common procedures include cerebral spinal fluid (CSF) assessment, a key component in the neurodiagnostic process and usually conducted through a lumbar puncture; analysis of biochemical markers, which can be useful to differentiate between the various etiologies for neurodegenerative conditions; biopsies, for rapidly progressive neurodegenerative conditions of unknown etiology; and genetic testing, guiding patient treatment and family planning. Many neuropathologic conditions have similar presentations at different stages of the diseases that can confound the diagnosis. A proper evaluation requires the use of diagnostic tools to better understand the disease process present in the patient and for evaluating potential outcomes and treatment modalities. Differentiating the disease impacting the life of a patient will allow the practitioner to manage patient and family expectations on disease progression and direct patients to any resources that are available.</jats:p>